The Scripps Translational Science Institute is sponsored by the National Institutes of Health and led by Scripps Health in La Jolla, Calif. Ali Torkamani, assistant professor and director of genome informatics, heads the project and is working on a wide range of research projects. They include:
• The Molecular Autopsy Study is searching for genes associated with sudden, unexplained death by sequencing and analyzing the DNA of adults, children and infants whose deaths cannot be explained using traditional medical investigative methods.
• The GIRAFFE Study seeks to identify a set of genetic mutations associated with atrial fibrillation, the most common type of irregular heartbeat. Those mutations would then be used to predict a risk of developing the potentially dangerous condition.
• The IDIOM Study uses DNA sequencing to look for the genetic causes and potential treatments of idiopathic diseases — those serious, rare and perplexing health conditions that defy diagnosis and standard treatment.
[For more on predictive analytics: ‘Moneyball’ Mindset Is Transforming Health Care]